Generally speaking, there are two kinds of granulating methods, wet granulation and dry granulation. Wet granulating requires the use of granulating liquid while dry granulating does not.
Pharmaland Technologies offers both dry granulator and wet granulator equipment. Wet process granulators are available in two configurations: high efficiency wet process and fluid bed drye
This machine is applicable for the pharmaceutical, food, and chemical industries, as a primary method of solid preparation. It is used to produce multiple granules, large granules, dense granules, instant porous granules, and dry materials in powder, granules, or paste. It is one of the preferred methods for pelletizing and drying for presence.
This machine contains a main engine and an auxiliary engine, with five systems, including cooling hot-air system, air purification system, charging and discharging system, automatic control system and air pipe line.
During the operation, the materials are added into the hopper, and heated to the boiling state by the purified hot air (negative pressure) from the bottom of the pelletizing chamber. Meanwhile, the granules are dried by the hot airflow, forming into ideal, porous and homogeneous ones. The whole process is conducted in airtight conditions.
Convenient operation, stable performance and rational structure. Adopts the PLC automatic control, with 8 featured functions:
The main engine can be linked directly with the former or latter equipment conveniently.
The out frame utilizes a ladder-type structure, resulting in convenient processing and maintainance.
It fully conforms with the GMP requirements of the pharmaceuitical industry.
Wet type granulators, also called wet mixing granulators are dedicated equipment used for the wet mixing granulating of powder, starch, adhesives and cream in the food, pharmaceutical, and chemical industries.
This is a newly designed machine which better meets the technical requirements of solid preparation production. It is made of austenitic stainless steel and equipped with an operating platform, stairs and a safety fence.
It has PLC and frequency speed controls.
Technical parameters can be designed according to the requirements of the users, with authentic reliable and original records.
It can either work separately or together with a matched line.
It fully conforms to the requirements of the GMP of the pharmacy industry.
Due to both the adequate stirring from the bottom and the adhesives (or cream) sprayed by pressure, the materials in the cone container are mixed into a moist and soft state. The high-speed cutting tool on the side turns the materials into uniform granules. The granules are straightened during the discharging of the material. By changing the screen, different granules can be made.
The main barrel: The tangential structure between the cylinder and the cone is good for stirring materials. The optimized angle between the stirring paddle and the parting tool ensures the optimized effect of mixing and granulating.
The cutting tool is installed aslant to the straight wall of the barrel, which increases the contacting area between the parting tool and the materials and improves the uniformity of the granules. Furthermore, the aslant installation of the parting tool can prevent the materials from being sprayed onto the cover of the barrel, avoiding the problem of the traditional cutting in older designs.
The granulator making machines are responsible for a number of tasks in the production process.
The dry granulation method has the advantage of being able to mix powders of different compositions and properties evenly. In addition, this method is suitable for drugs that are difficult to be added in solution or suspension form. The dry granulation process is also advantageous in that it can reduce dust generation and improve working conditions. However, this method has the disadvantage of being time-consuming and requiring a certain level of skill.
The dry granulation process is generally divided into two steps: compaction and milling. In the compaction step, the powder mixture is compressed into a desired shape. In the milling step, the compact is pulverized and granulated to the desired particle size.
The dry granulation method has been used for centuries in the preparation of traditional Chinese medicines. In recent years, this method has been increasingly used in Western countries due to its advantages.
If you are interested in learning more about dry granulation, please contact us. We would be happy to discuss this topic with you in further detail.
Dry granulation and wet granulation are both methods of preparing granules. In dry granulation, the raw material is compressed into granules without adding any water or binders. In wet granulation, a binder is added to the drug powder and the powder is agglomerated by the bridge or cohesion of the binder to prepare granules. Subsequent drying is required. dry granulation is a simpler process and does not require the addition of any binders or other materials, while wet granulation may be necessary for some drugs. Ultimately, the choice of granulation method depends on the properties of the raw material and the desired characteristics of the finished product.
Standard seaworthy wooden case packing.
If there are any special requirements on packing, we can discuss further.
NOTE: The packaging is not designed for long term outside storage.
Machines are wrapped with plastic film for protection
Standard wood packaging for exporting
Loading goods by forklift
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One-year limited warranty and lifetime service are provided.
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I appreciate their quick response and give me clear guidance during installation, we are happy to work with this high-speed capsule filling machine.
Robert
They keep me updated during the machine production, doing well inspection before shipment, show me the video and ship everything on time. Good Job!
Zed
It is amazing that they prepared all documents which we needed in advance for customs clearance, some I didn't even know in advance, very professional!
Maria
This is the second time to buy a machine from PAG, they are the only supplier we trust, very good machine and they are very professional in customizing the production line for us.
Alfred
Very good experience to work with PAG, both the sales and their service are reliable, and the tablet press machine is easy to use and maintain.
Kenny
Pharmaland Technologies is a technology-based subsidiary of PAG Group, integrating manufacturing and trade, that specializes in supplying pharmaceutical and packaging machines.
The predecessor of PAG group is Honson Pharmatech, established in Canada in 1995.
Pharmaland mainly provides comprehensive solutions for manufacturers of all sizes, providing safe, GMP-compliant “turnkey” engineering equipment. With rich experience in pharmaceutical production, we not only provide customers with suitable machinery, but also provide suggestions for common processes.
We export machines worldwide, including Europe, America, Africa, and Asia.
Our machines have passed ISO 9001 quality system certification and CE certification. ”Quality First, Service Oriented” is our business philosophy. We are committed to providing high-quality pharmaceutical and packaging equipment and solutions for global manufacturers.
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